OMP and pancreatic neoplasm: Therefore we investigated the one- and two-dimensional dose-effect relationships of OMP alone or in combination with 5-fluorouracile (5-FU) or gemcitabine (GEM) in the well characterized human pancreatic cancer cell lines MiaPaCa-2, ASPC-1, Colo357, Panc1, Panc89 and PancTu1 in vitro [19]–[21].