The observed upregulation of c-fos, Klf2, Nr4a3, Klf4 has been confirmed in an independent study that also reported the upregulation of Leiomodin 2 (Lmod2) in the thalamus of male rats following acute PCP administration at PND 50 but not at PND 8, suggesting that Lmod2 may be involved in the age-dependent onset of drug-induced schizophrenia-like psychosis [47]. This evidence concerns the gene LMOD2 and schizophrenia.