Exposure cut-points for NHANES III are from Venn and Britton (2007); those for the ROC curve were calculated following the method of Fawcett (2006). aLogistic regression model adjusted for age, sex, race, educational level, job title, recruitment method, former smoking, obesity, high blood pressure, history of heart disease, COPD, chronic rhinitis, and hay fever. bhs-CRP median, 0.93 mg/L. chs-CRP highest tertile, > 1.5 mg/L. dIL-6 median, 1.38 pg/mL. esICAM-1 median, 246.1 ng/mL. The gene discussed is CRP; the disease is seasonal allergic rhinitis.