It is particularly noteworthy that 24 out of 33 (72.7%) glioma samples that exhibited high SPHK1 expression displayed low expression of Bim, in contrast to the high level Bim expression in 34 out of the 49 (69.4%) glioma samples with low SPHK1 expression (Figure 4C). The gene discussed is BCL2L11; the disease is glioma.