Indeed, as can be seen in Figure 9C, similar HIV-1-specific CD8+ T cell lymphoproliferative responses were obtained in the model of optimal infection (0.3 PFU/MDDC) and in a model where a ratio of 1∶2 (apoptotic bodies: uninfected MDDC) was used, with no significant differences between both experiments (optimal dose: 6.97% of CD8+ proliferation; apoptotic bodies: 6.81% of CD8+ proliferation, p = 0.8383). This evidence concerns the gene CD8A and infection.