Similarly,NAC and catalase inhibited the induction of ORF65 proteins by these cytokines.Since KS tumors contain abundant infiltration of proinflammatory immune cellssuch as monocytes, we further examined the effects of proinflammatory andproangiogenic cytokines on KSHV reactivation in the presence of monocytic cellsU937 (Figure 4E). Here, CAT is linked to Kaposi's sarcoma.