NFKB1 and digestive system disorder: In order to investigate the potential targets involved in the boeravinone G antioxidant/genoprotective action, we have analyzed the effect of this plant ingredient on an antioxidant defence enzyme (SOD) and on two signal transduction pathways (MAP kinase and NF-kB) that play a pivotal role in the oxidative stress-induced gastrointestinal disorders [41], [42].