However, serum ULBP2 levels were strikingly elevated in PC patients compared to those in CRC (200.2±168.6 versus 70.6±73.8 pg/mL, p<0.0001) and NPC (200.2±168.6 versus 65.5±74.3 pg/mL, p<0.0001) patients (Fig. 5A). Here, ULBP2 is linked to pachyonychia congenita.