[6], [7], [8], [9]. Among these proteins, we have found that parathyroid hormone-related protein (PTHrP) and its receptor are constitutively expressed in this tumor [10]. In some pathways, such as the Indian hedgehog (Ihh) pathway, Runx2 and PTHrP have been shown to regulate each other in a reciprocal fashion [11], [12], [13]. This evidence concerns the gene RUNX2 and neoplasm.