Indeed, (1,3)-beta-D-glucan is ubiquitous in nature contamination can be caused by concomitant bacterial bloodstream infections, presence of surgical gauzes, use of glucan-containing membranes for haemofiltration and use of albumin or immunoglobulins.62 For example, in a study that focused on the validation of the Candida Score, (1,3)-beta-D-glucan testing was performed in a subgroup of 240 patients with Candida species colonisation or invasive fungal infection.53 For a cut-off of 75 pg/ml, good sensitivity of 77.8% was reported, but the specificity was low (52.7%). Here, ALB is linked to fungal infectious disease.