Autosomal recessive CGD (AR-CGD), seen in the remaining 35% cases, arise due to mutations of the other components of the NADH oxidase (except p40phox and Rac which are yet to be associated with any CGD phenotype) [22]: these include- p22phox , p67phox and p47phox . This evidence concerns the gene NCF1 and chronic granulomatous disease.