In this respect, it is noteworthy that when tested in the same conditions, P122-131, which is another peptide derived from the C-terminal part of HARP inhibiting the growth of DU145 and LNCap prostate cancer cells [33], acted also on PC-3 cells but in a lesser extent with only 22% inhibition for 1 μM (data not shown). Here, PTN is linked to Familial prostate cancer.