An investigation was therefore made of the effects of Amaranthus on the regression of atherosclerosis and serum lipids (cholesterol, triglyceride and LDL-cholesterol, HDL-C, ApolipoproteinB(apoB), apolipoproteinA(apoA), malondialdehyde (MDA), hs-C-reactive protein (hs-CRP) as well as atherosclerosis index (AI) and OX-LDL in rabbits. This evidence concerns the gene APOB and atherosclerosis.