Despite these differences, the decline in the activity of Cdk2 within 24 h of exposure to MF was a commonality among the 10 cell lines studied (Figure 4), as we have shown in ovarian cancer cells for MF [13] and more recently for two other antiprogestins, ORG-31710 and CDB-2914 [46]. This evidence concerns the gene CDK2 and ovarian carcinoma.