The resulting group of genes includednegative regulators of inflammation, such as the psoriasis susceptibility geneTNFAIP3 [21], [37] and theNotch ligand jagged 2 [38], and also genes regulating epidermal differentiation,such as the transcription factor AP2-α (TFAP2A) [39], and the apoptosis-inducing FASmolecule. This evidence concerns the gene TFAP2A and psoriasis.