INS and polycystic ovary syndrome: PCOS women carriers of haplotype 2 had increased insulin (non-carriers: 78.0 (92.4) vs. carriers: 108.0 (120.9) pmol/l; P = 0.006), HOMA-IR (non-carriers: 1.76 (1.90) vs. carriers: 2.33 (2.43); P = 0.003) and HOMA-%B (non-carriers: 146.3 (97.7) vs. carriers: 176.6 (113.7); P = 0.002).