CD4 and HIV infectious disease: In the multivariate analysis only African (IRR: 4.3; 95% CI: 2.6-7.3; p-value < 0.001) and Asian (IRR: 5.7; 95% CI: 3.2-10.1; p-value < 0.001) origin, route of HIV infection (heterosexual (IRR: 1.9; 95% CI: 1.0-3.5; p-value: 0.048), IDU (IRR: 3.0; 95% CI: 1.5-6.2; p-value: 0.003) and other (IRR: 2.4; 95% CI: 1.2-4.9; p-value: 0.020)) and CD4 cell count ≤ 200 cells/μL at HIV diagnosis (IRR: 1.6; 95% CI: 1.1-2.2; p-value: 0.005) preserved a statistically significant association with increased risk of TB diagnosis.