FRG1 and facioscapulohumeral muscular dystrophy: Acting under the assumption that overexpression of FRG1, FRG2 or ANT1 plays a causative role in the development of FSHD, transgenic mice were generated expressing each of these individual genes under the human skeletal actin promoter, specific for expression in muscle, which resulted in the identification of a potential mouse model for FSHD.