Hemmann et al. [24] reported that ABPA and Aspergillus-sensitive patients have elevated IgE antibodies to recombinant Aspergillus Asp f1, Asp f3, Asp f4, and Asp f6 allergens, and that IgE levels to Asp f4 and Asp f6 is highly specific for ABPA in CF patients. This evidence concerns the gene IGHE and cystic fibrosis.