Some of those diseases have similarly been shown to favourably influence the course of malaria, i.e. sickle-cell trait, beta-thalassaemia-trait, homozygous Hb-C and G6PD-deficiency [22,46-50] as well as iron deficiency [21]. This evidence concerns the gene GSTM1 and hyperinsulinemic hypoglycemia, familial, 4.