MTOR and malignant colon neoplasm: We found that 14 miRNAs were associated with protein ubiquitination pathway, all 15 miRNAs were in polyamine regulation in colon cancer, 11 miRNAs were associated with purine metabolism, 2 miRNAs were associated with circadian rhythm signaling, 4 miRNAs each were associated with hypoxia signaling in cardiovascular system and cdc42 signaling, and 7 miRNAs each were associated with pyrimidine metabolism, mTOR signaling or NRF2-mediated oxidative stress response or xenobiotic metabolism signaling along and their targets are mentioned in the last column of Table 6.