PRKN and Parkinson disease: Mutations in a number of genes including α-synuclein (SNCA), Parkin, Leucine-Rich-Repeat-Kinase 2 (LRRK2), Phosphatase and Tensin (PTEN) Homolog-Induced Putative Kinase 1 (PINK1) and DJ-1 among others can cause PD or increase the risk of PD [3-6].