Recent data have shown that several viruses, including herpes simplex virus type 1 (HSV-1), polyomavirus, human papillomavirus (HPV), and human immunodeficiency virus type 1 (HIV-1) require the activation of ATM and/or downstream proteins for a fully permissive infection [3], [4], [5], [6], [7]. The gene discussed is ATM; the disease is infection.