S100B and infection: Also, strong immune pressure upon neighbouring epitopes such as B57-KF9 Nef in the first few weeks post-infection [13] or on epitopes overlapping with FL8, such as B60-KL9 [51], A2-FL11, A3-AK9, A3-DK9, A24-HL9, may alter the generation and consequent immunogenicity of FL8.