A search of the Oncomine database (December 09) revealed that PRL-3 was significantly overexpressed in FLT3-ITD positive AML as compared to FLT3-ITD negative AML (study name: Valk_leukemia, 78 vs 206 cases, p<0.001, Figure S3) [15], indicating a possible association between PRL-3 expression and FLT3-ITD mutation. This evidence concerns the gene FLT3 and acute myeloid leukemia.