Note, lysyl oxidase like 1 (Loxl1) and proteoglycan 4 (Prg4) are reduced in plasma from confounders and increased in both breast and pancreatic tumor-bearing mice, while fatty acid synthase (Fasn) and lipocalin2 (Lcn2) are increased in both confounders and cancer models (Table S1). Here, PRG4 is linked to pancreatic neoplasm.