ADIPOQ and metabolic syndrome: In men, the ROC curve analyses showed that the best marker of the MetS-associated variables (Presence of MetS, HOMA-IR§ >1.98, and serum HMW adiponectin <2.97 μg/mL) was TG/HDL-C ratio, with the AUC for presence of MetS (AUC, 0.82; 95% CI, 0.77-0.87), HOMA-IR (AUC, 0.75; 95% CI, 0.70-0.80), and serum HMW adiponectin (AUC, 0.67; 95% CI, 0.63-0.71), respectively (Table 4).