Both Arg1flox/flox;Tie 2-cre and Arg1+/+;Tie 2-cre mice were able to expel the worms, with almost all mice completely clear of parasites by day 35 p.i. C57BL/6 mice were also infected with around 175 infective T. muris eggs and treated with nor-NOHA by i.p. injection up to day 21 post-infection to inhibit all arginases including arginase 1. Here, TIE1 is linked to infection.