STAT3 and neoplasm: In our study, the expression of STAT3 in soft tissue tumors showed significant association with tumor size (OR = 19.38, 95% CI: 2.25-166.5, P = 0.003), tumor location (OR = 9.6, 95% CI:1.48-62.15, P = 0.025), plane of the tumor (OR = 8.05, 95% CI:1.62-39.8, P = 0.011), tumor circumscription (P = 0.005) and tumor necrosis (OR = 18.13, 95% CI: 2.28-143.6, P = 0.001).