IFNG and nasopharyngeal carcinoma: Based on these superior attributes, we developed a recombinant minicircle vector carrying the human IFNγ gene that had antiproliferative and antitumor effects against NPC in vitro and in vivo and also demonstrated that the antiproliferative effects of IFNγ gene transfer on NPC cell lines could be attributed to G0-G1 arrest and apoptosis [13].