As shown in Figure 6C, the mAbs to the heparan sulphate-interacting CD11b expressed on B cells, and the LEEP-CAM integrin expressed on epithelial cells both independently caused a significant reduction in transfer infection by up to 45%; in contrast, blocking mAbs to αVβ6 and α5β1 integrins did not inhibit transfer infection. The gene discussed is ITGAM; the disease is infection.