We have recently shown that Mitostatin is ubiquitously expressed in normal humantissues, but its levels are markedly attenuated in advanced stages of breast andbladder cancers [13].To investigate Mitostatin expression in prostate cancers, we evaluated byqRT-PCR analysis 10 matched normal-cancer samples and by immunohistochemistry(IHC) three tissue microarrays composed of 293 specimens including 124 prostatecancers and 43 normal counterparts. The gene discussed is TCHP; the disease is prostate carcinoma.