CYP1B1 and congenital glaucoma: Recently, Hollander and co-workers tried to correlate CYP1B1 mutations with the degree of angle dysgenesis observed histologically and disease severity in terms of age at diagnosis and difficulty in controlling IOP in six congenital glaucoma patients.61 Their findings suggested that CYP1B1 mutations could be classified based on histological findings, which may be used to correlate these mutations with disease severity.