The following findings were relevant to ICU patients: pleural effusion (P = 0.006), laboratory test results indicated higher prevalence of leukopenia, thrombocytopenia and increased level of Cr, elevated liver enzymes, CPK and LDH level (P < 0.05), low O2 saturation level (P < 0.001) [Table 2]. Here, PIK3C2A is linked to Pleural effusion.