RHO and Patent ductus arteriosus: We demonstrated thattyrosine 23 phosphorylation resulting in surface expression of ANXA2 is requiredfor TGFβ-induced, Rho-mediated epithelial-mesenchymal transition (EMT),linking the cellular function of ANXA2 which was previously shown to beassociated with small GTPase-regulated cytoskeletal rearrangements, to the EMTprocess in PDA.