To test this, weeluted the cell surface fraction of ANXA2 from Panc10.05 PDA cells, which havecell surface localization of ANXA2 (FigureS4 andTableS1), and found the cell surface fraction of the ANXA2protein is in fact a tyrosine-phosphorylated protein (Figure 2A). This evidence concerns the gene ANXA2 and Patent ductus arteriosus.