MAPT and corticobasal degeneration disorder: Missense and exon 10 splicing mutations in MAPT lead to frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17), whereas a region of LD within MAPT, known as the H1 haplotype is associated with increased risk of taupathies, namely, corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) compared with the (reviewed in [54]).