GCKR and type 2 diabetes mellitus: In a study of a population-based sample of Han Chinese individuals, the GCKR rs780094 A allele was found to be significantly associated with a reduced risk of impaired fasting glucose (IFG) and type 2 diabetes, decreased fasting glucose, increased homeostasis model assessment of beta cell function (HOMA-B), and fasting triglyceride levels; GCKR rs1260326 displayed similar associations [12].