Other genetic causes of high ferritin levels in a child include juvenile hemochromatosis, an autosomal recessive disorder caused by the mutation of HJV (HFE2) gene [11], or, more rarely, of HAMP (HEPC) gene [12]; in contrast with hyperferritinemia-cataract syndrome, it is characterized by an early-onset iron overload, causing liver cirrhosis, cardiomyopathy and endocrine complications in the second or third decade of life; this condition may cause increased levels of ferritin and transferrin saturation in children [13,14]. The gene discussed is HJV; the disease is Tangier disease.