To further examine the interaction between endogenous CK2α and Twist protein in SCCHN cells, the FaDu cell line was chosen because it expresses a high basal level of CK2 protein; HN31 SCCHN cells that stably express Myc-tagged Twist (HN31 Myc-Twist SCCHN cells) were established for immunoprecipitation purposes because of the poor performance of the commercially available Twist antibodies. This evidence concerns the gene MYC and head and neck squamous cell carcinoma.