Most interestingly, in solid tumors derived from mice treated MNU and H. pylori, the frequency of CD4+FoxP3+ Treg-cells was an average of 9.095% of the total TIL, suggesting that these accumulated Treg-cells may serve as a common immune evasion mechanism to impede immunosurveillance against autologous tumor cells. This evidence concerns the gene CD4 and neoplasm.