After treatment of DT or DTmu for 14 days, we observed that the selective depletion of TAMs evidently inhibited the production of CCL20 by CMT93GFP mouse tumor cells, suggesting that TAMs are not only the major source of CCL20 but also distinctly contribute to the release of CCL20 from CRC cells in mice (Figure 5E). The gene discussed is CCL20; the disease is colorectal carcinoma.