In conclusion, we recommend cART initiation after 15 d of TB treatment for those withCD4 cell counts≤100 cells/μl and by day 60 for individuals with CD4 cellcounts of 101–200 cells/μl, and advocate for TB treatment to be used asan opportunity to refer and retain HIV-infected individuals in care, regardless ofCD4 cell count. The gene discussed is CD4; the disease is tuberculosis.