Adegbite et al8 reviewed the charts of 111 individuals who had cutaneous and subcutaneous ossification for 8 characteristics: age of onset of HO, presence and location of HO, depth of HO, type of HO, progression of HO, features of AHO, parathyroid hormone resistance, and GNAS mutation analysis. The gene discussed is GNAS; the disease is pseudohypoparathyroidism type 1A.