By K-W analysis for the expression level of ER81, we found a statistical significance between NBT and HUT (P < .05) and HUT and ADH (P < .05), but no statistical significance was found between ADH and DCIS (P > .05) or DCIS and IDC (P > .05) (Table 2 and Figures 4, 5). The gene discussed is AVP; the disease is ductal breast carcinoma in situ.