MRC1 and adenoma: They reported that MMR gene mutation carriers who are overweight or obese (current BMI ⩾25 kg m–2) had higher risk of adenomas compared with those with normal BMI (<25 kg m–2) for men (HR: 8.72; 95% CI: 2.06–36.96), but not for women (HR: 0.75; 95% CI: 0.19–3.07).