The expression of STS and EST1E1 evaluated in breast carcinomas were also correlated with clinicopathological parameters such as estrogen receptor α (ER-α), estrogen receptor β(ER-β), progesterone receptor A (PR-A), progesterone receptor B (PR-B) and cell division control protein 47 (CDC47) expression as well as type and stage of the tumors and age and estimated menopausal status of the patients at surgery. This evidence concerns the gene ESR1 and breast carcinoma.