Evaluation of the chromosomal region 1q21–1q23, frequently amplified in primary liposarcomas, by fluorescence in situ hybridization and comparative genomic hybridization reduced the list of candidate oncogenes contained by this amplicon to two genes: the activating transcription factor 6 (atf6) and the dual specificity phosphatase 12 (dusp12) [1]. This evidence concerns the gene ATF6 and liposarcoma.