The aim of this study was therefore to analyze expression of the full length AR (ARfl) and its clinically most abundant splice variants here termed AR-V1, AR-V7 [14] (also referred to as AR3 [13], [17], and AR-V567es [16] in HN and CRPC bone metastases in comparison to expression in primary PC and in non-malignant prostate tissue. The gene discussed is AR; the disease is pachyonychia congenita.