Whereas p53−/− thymic lymphomas have been reported to rarely harbor chromosomal translocations [61], [62], two of the three examined Rnf168−/−p53−/− B-cell lymphomas carried clonal reciprocal translocations between chromosomes 12 and 15 [t(12;15) and t(15;12)] (Table S4 and Figure 8H). The gene discussed is RNF168; the disease is thymus lymphoma.