SOCS3 and allergic asthma: In a finding similar to ours, McGee et al. observed that the therapeutic effect of FMS-like tyrosine kinase 3 (Flt3) in reversing the hallmarks of allergic asthma in a mouse model is mediated by decreasing TGF-β, which in turn decreases Th17 cells and the expression of SOCS1 and SOCS3 in the lung of asthmatic mice [30].