By luciferase assay, miR-124-1 has been shown to downregulate CDK6 translation by binding on the 3′ untranslated region (3′ UTR) of the CDK6 mRNA, and also reduce the retinoblastoma protein phosphorylation, thereby demonstrating the tumour suppressor role of miR-124-1[14]. Here, CDK6 is linked to neoplasm.